(Tretinoin cream)

Description:

Tretinoin 0.05% in a smooth hydrophilic cream base

Indications:

Treatment of dry skin and related conditions.

Contra-indications:

Hypersensitivity to tretinoin or any of the ingredients in the formulation.

Precautions:

Do not swallow and avoid contact with mucous membranes or open wounds. Retiniva Cream should not be applied to the eyes, mouth, lips, mucosa, or angles of the nose. If severe irritation occurs, especially at the early stage of therapy, the patient should be advised to discontinue temporarily or reduce the frequency of application.

Adverse Reactions:

Retiniva Cream is generally well tolerated after nightly application. Side effects have been limited to mild irritation, evidenced by peeling and erythema, especially in the early stage of treatment. Some patients may experience a sensation of warmth or slight stinging after application of the drug.

Dosage and Administration:

Retiniva Cream should be applied sparingly to the affected areas once daily at bedtime. Treatment with tretinoin should be individualised according to tolerance and response.

Begin treatment program slowly.

a. Wash the affected areas prior to any applications with mild soap-free cleansers (eg. DermaVeen Dry Skin Cleansing Bar or similar). Pat dry.

b. First night apply, leave for five minutes, then wash off.

c. Second night apply, leave for ten minutes, then wash off.

d. Third, fourth, fifth and sixth nights, increase the treatment time each night by 30 minutes until the application is left on for two hours.

e. If after two hours application, no redness or irritation has developed on the skin the following day, then the application may be left on overnight and washed off next morning.

f. If excessive skin reactions occur, adjust the schedule to alternate nights until the skin accommodates.

Certain types of skin could be too sensitive to Retiniva Cream. Patients with very sensitive skin should consult a dermatologist before commencing treatment.

Storage:

Store below 25°C.

Pack:

Cream 20 g tube

LINK: http://www.inhousedrugstore.co.uk/skin-care/retina-information.html